Fig. 1
From: Advances in surgical applications of growth factors for wound healing

Pressure ulcer debridement. a This is a highly infected sacral pressure ulcer. Prior to the application of any growth factors, contaminated wounds should be meticulously and completely debrided. b This is the same pressure ulcer after debridement. Debridement of pressure ulcers is a safe and effective technique to make growth factor receptors respond to exogenous topical treatment