Fig. 3

A 76-year-old-male presented with a one-and-a-half-year history of a chronic venous ulcer on his left lower leg. a The wound was initially managed with classical dressings prior to arrival at our clinic. b After six applications of leukocyte- and platelet-rich fibrin (L-PRF), c wound granulation closed over the wound. d With 24 applications of L-PRF, a good level of wound contraction was noted and the wound was nearly epithelized. e The complex chronic venous leg wound was uneventfully healed